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Kossiakoff, Anthony

One or more keywords matched the following items that are connected to Kossiakoff, Anthony

Item Type	Name
Concept	Calmodulin-Binding Proteins
Concept	Protein Binding
Concept	RNA-Binding Proteins
Concept	GTP-Binding Protein alpha Subunits, Gs
Concept	GTP-Binding Protein alpha Subunits, Gi-Go
Concept	GTP-Binding Proteins
Concept	Cation Transport Proteins
Concept	Carrier Proteins
Concept	Membrane Transport Proteins
Concept	Maltose-Binding Proteins
Academic Article	Crystallization and preliminary X-ray analysis of a 1:1 complex between a designed monomeric interferon-gamma and its soluble receptor.
Academic Article	Probing intermolecular backbone H-bonding in serine proteinase-protein inhibitor complexes.
Academic Article	Analysis of solvent structure in proteins using neutron D2O-H2O solvent maps: pattern of primary and secondary hydration of trypsin.
Academic Article	Structural basis for cytokine hormone-receptor recognition and receptor activation.
Academic Article	Solvent structure in crystals of trypsin determined by X-ray and neutron diffraction.
Academic Article	Site2 binding energetics of the regulatory step of growth hormone-induced receptor homodimerization.
Academic Article	Functional promiscuity of squirrel monkey growth hormone receptor toward both primate and nonprimate growth hormones.
Academic Article	The functional binding epitope of a high affinity variant of human growth hormone mapped by shotgun alanine-scanning mutagenesis: insights into the mechanisms responsible for improved affinity.
Academic Article	Crystals of the complex between human growth hormone and the extracellular domain of its receptor.
Academic Article	Crystal structure and site 1 binding energetics of human placental lactogen.
Academic Article	Dissecting the binding energy epitope of a high-affinity variant of human growth hormone: cooperative and additive effects from combining mutations from independently selected phage display mutagenesis libraries.
Academic Article	The high- and low-affinity receptor binding sites of growth hormone are allosterically coupled.
Academic Article	Alternative views of functional protein binding epitopes obtained by combinatorial shotgun scanning mutagenesis.
Academic Article	Comprehensive and quantitative mapping of energy landscapes for protein-protein interactions by rapid combinatorial scanning.
Academic Article	Exploring the capacity of minimalist protein interfaces: interface energetics and affinity maturation to picomolar KD of a single-domain antibody with a flat paratope.
Academic Article	Understanding mechanisms governing protein-protein interactions from synthetic binding interfaces.
Academic Article	Intramolecular cooperativity in a protein binding site assessed by combinatorial shotgun scanning mutagenesis.
Academic Article	Structure of bovine trypsinogen at 1.9 A resolution.
Academic Article	Crystal structure of full-length KcsA in its closed conformation.
Academic Article	Allosteric control of ligand-binding affinity using engineered conformation-specific effector proteins.
Academic Article	Effect of protein packing structure on side-chain methyl rotor conformations.
Academic Article	Determination of the energetics governing the regulatory step in growth hormone-induced receptor homodimerization.
Academic Article	The structural basis for biological signaling, regulation, and specificity in the growth hormone-prolactin system of hormones and receptors.
Academic Article	Principal determinants leading to transition state formation of a protein-protein complex, orientation trumps side-chain interactions.
Academic Article	An engineered substance P variant for receptor-mediated delivery of synthetic antibodies into tumor cells.
Academic Article	Characterization of engineered actin binding proteins that control filament assembly and structure.
Academic Article	Structure of active ß-arrestin-1 bound to a G-protein-coupled receptor phosphopeptide.
Academic Article	Visualization of arrestin recruitment by a G-protein-coupled receptor.
Academic Article	Applications for an engineered Protein-G variant with a pH controllable affinity to antibody fragments.
Academic Article	Human-chromatin-related protein interactions identify a demethylase complex required for chromosome segregation.
Academic Article	Engineering Synthetic Antibody Inhibitors Specific for LD2 or LD4 Motifs of Paxillin.
Academic Article	A New Versatile Immobilization Tag Based on the Ultra High Affinity and Reversibility of the Calmodulin-Calmodulin Binding Peptide Interaction.
Academic Article	A YidC-like Protein in the Archaeal Plasma Membrane.
Academic Article	Architecture of the fungal nuclear pore inner ring complex.
Academic Article	Specific Recognition of a Single-Stranded RNA Sequence by a Synthetic Antibody Fragment.
Academic Article	The Preserved HTH-Docking Cleft of HIV-1 Integrase Is Functionally Critical.
Academic Article	Engineered synthetic antibodies as probes to quantify the energetic contributions of ligand binding to conformational changes in proteins.
Academic Article	Cryo-EM structure of human rhodopsin bound to an inhibitory G protein.
Academic Article	Structural basis for activation of SAGA histone acetyltransferase Gcn5 by partner subunit Ada2.
Academic Article	Ensemble cryoEM elucidates the mechanism of insulin capture and degradation by human insulin degrading enzyme.
Academic Article	The structure of the C-terminal domain of the nucleoprotein from the Bundibugyo strain of the Ebola virus in complex with a pan-specific synthetic Fab.
Academic Article	Development of "Plug and Play" Fiducial Marks for Structural Studies of GPCR Signaling Complexes by Single-Particle Cryo-EM.
Academic Article	Structure and drug resistance of the Plasmodium falciparum transporter PfCRT.
Academic Article	Structure and mechanism of the ER-based glucosyltransferase ALG6.
Academic Article	Synthetic antibodies against BRIL as universal fiducial marks for single-particle cryoEM structure determination of membrane proteins.
Academic Article	Recognition of an a-helical hairpin in P22 large terminase by a synthetic antibody fragment.
Academic Article	Development of a universal nanobody-binding Fab module for fiducial-assisted cryo-EM studies of membrane proteins.
Academic Article	Structures of atypical chemokine receptor 3 reveal the basis for its promiscuity and signaling bias.
Academic Article	Development, structure, and mechanism of synthetic antibodies that target claudin and Clostridium perfringens enterotoxin complexes.
Grant	Chaperone Assisted Crystallography
Academic Article	Conformation-specific Synthetic Antibodies Discriminate Multiple Functional States of the Ion Channel CorA.
Academic Article	Structure of human drug transporters OATP1B1 and OATP1B3.

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Carrier Proteins